Which of the following RNA\'s is most likely to give a stem and loop structure?

Question

Which of the following RNA's is most likely to give a stem and loop structure? 5'-GCCUUAGGGUACCCCCUAAGCC -3' 5-AACCGGUUAACCGGUUAACCG-3' 5-UUUUUUUUUCCCCCCCCCCCC-3' 5-AAACCGGUUAAACCGGUUAA-3' 5-GGCGGCAAAGGCGGCAAAGGC-3' Which of the following stem loop structures is correct for the sequence 5'-AACCGGTTCGAUAAACCGGUU-3' ? The anticodon loop of a tRNA is shown below, with the anticodon in red. Which amino acid will be bound to this tRNA? Based on wobble, which of the changes to the anticodon above will preserve the identity of the encoded amino acid: C changed to G A changed to G C changed to A A changed to U U changed to C

Explanation / Answer

1. (a)

2. (b)

3. (c). The 3' end of tRNA binds to 5' end of mRAN. So, the mRNA codon is GUA and anticodon is CAU not UAC

4. (e). Wobble hypothesis states that the third position (3') of the codon on mRNA and the first position (5') of the anticodon on tRNA are bound less tightly than the other pair and therefore, offer unusual base combinations.

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