In the lac operon, what are the likely effects on operon gene transcription of t
ID: 67590 • Letter: I
Question
In the lac operon, what are the likely effects on operon gene transcription of the mutations identified below?
Mutation of consensus sequence in the lac promoter
Mutation of the repressor binding site on the operator sequence
Mutation of the lac I gene affecting the allosteric site of the protein
Mutation of the CAP binding site of the lac promoter
Mutation of the lac I gene affecting the DNA-binding site of the protein
A. Transcription is blocked.
B. Transcription is constitutive.
C. No effect on transcription
Explanation / Answer
Mutation of consensus sequence in the lac promoter -----------> A. Transcription is blocked.
Mutation of the repressor binding site on the operator sequence -----------> B. Transcription is constitutive.
Mutation of the lac I gene affecting the allosteric site of the protein -----------> A. Transcription is blocked.
Mutation of the CAP (catabolite activator protein) binding site of the lac promoter -------------> A. Transcription is blocked.
Mutation of the lac I gene affecting the DNA-binding site of the protein ------------> B. Transcription is constitutive.
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