being used (the acetate anion) is a relatively moderate anionic nucleophile. Eve

Question

being used (the acetate anion) is a relatively moderate anionic nucleophile. Even still, i order to obtain a good yield on this reaction in a short time we must heat it to 130 °C. SN2 displacement of a primaryl alkyl bromide DMF :Br O : : Br OR : Br acetate anion 1-bromo-3-methylbutane (isopentyl bromide) bromide anion isopentyl acetate OR butyl acetate OR 1-bromobutane nucleophile substrate product leaving group A typical organic reaction involves three general steps. First, the reaction itself i performed. The reagents are mixed in the correct amounts and solvent is added (typically to dissolve the reactants to promote intimate mixing of the reagents. The reaction is the allowed to stir at a specific temperature for a specific period of time. Some reactions nee to be run at lower temperatures, some at elevated temperatures, some run for 5 minutes and some will run for 5 days. Some reactions are sensitive to moisture or oxygen and nee to be kept in an inert atmosphere (like N2 or Ar). The second step in a reaction is what i informally called the "work-up". In the work-up the product is separated from. the bulk the other materials used in the reaction. Typically an extraction is done first with an organi solvent (diethyl ether and dichloromethane are commonly used) to separate any organi soluble compounds from aqueous soluble materials. Then washes of the organic laye might be performed to remove any acidic or basic impurities. Then a drying agent (lik MgSO4 or Na2SO4) is added to the organic layer to sufficiently remove traces of wate This is then filtered and the organic solvent is removed (typically with a rotary evaporator The final step in a reaction is the purification. The material that remains after evaporatic of the organic solvent typically include unreacted starting compounds, unwanted sic products, and decomposition products. Since the goal is to isolate the intended product pu in the absence of other materials, the purification step is very important. Common metho for purification include distillation, recrystallization, or some type of preparati chromatography Special note on heating organic reactions: Organic reactions are often run in solvent e solvent plays a critical role in an organic reaction and without it most reactions woul fail. Any reaction that uses a sn as one inhe

Explanation / Answer

The rate of the reaction is fast with alkyl iodide compared to alkyl bromide becuase iodine is a good leaving group. Sn2 reaction is dependent on concentration of alkyl halide and nucleophile. Therefore Sn2 reaction fast with alkyl iodide.

Related Questions

Navigate

• Browse (All)
• Browse B
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.