In this reaction, nucleophillic addition takes place.Nucleophille attacks on car

Question

In this reaction, nucleophillic addition takes place.Nucleophille attacks on carbonyl Carbon after that electrophille adds on Carbonyl Oxygen . sp2 C after nucleophillic addition changes to sp3. Nucleophillic attack can takes place from topside(re) as well as from bottom side(si). It depends upon the steric hinderance around the Carbonyl group in carbonyl compound.

In present case ,CH3CH2- of grignard reagent attacks on sp2 hybridised C of carbonyl group, as it is planar so attack can takes place from top side(re) or from bottom side (si), it depends upon the steric hindrance.

In case of camphor ,topside attack is not favourable due to steric crowding of bridge head alkyl groups on Carbon

So attack will take place from bottom side (si) and the resulting product will form.

Explanation / Answer

?? which will it attack

Question Anonymous Asked about 1 hours ago ? ? ? detail Question Anonymous . Asked about 2 hours a… ? 77 ?? answer detail?what's re si 6. When camphor undergoes nucleophilic attack by CH3CH2MgB, the major produc is the one in which the Grignard reagent has added ende. Explain the stereoselectivity dbserved Which face of the carbonyl carbon, re or si, was attacked? I CH-CH Mghr OH CH CH

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