Question IX. RhoGAM [Rho(D) immune globulin] is administered in order to [comple

Question

Question IX. RhoGAM [Rho(D) immune globulin] is administered in order to [complete the sentence and assess each subsequent statement (68-73) as either factually correct (= “true”) or incorrect (= “false”)]:
68. stimulate only anti-RhD IgM production in pregnant RhD-negative women.

69. cause selective removal of anti-RhD memory B cells from the maternal circulation in pregnant RhD-negative women.

70. inhibit immune responses to RhD antigen in pregnant and postpartum RhD-negative women.

71. block transcytosis of IgG to fetal circulation by interfering with FcRn function in pregnant RhD-negative women.
72. prevent hemolytic anemia of the newborn.
73. treat primary immune thrombocytopenia.

Explanation / Answer

68. True but this has a very bad side effect as the Rh negative blood will create an immune system the destroys the positive Rh blood resulting to anemia, kidney or liver failure.

69. False. On the other hand the administering Rhd positive in a pregnant women with Rhd-negative would stimulate anti-D antibodies and the memory cells of the mother.

70. True. The adminteration of RhoGAM gradually brings the anti-RhD to zero

71. True. If RhoD is not administered the fetal blood enters the mothers circulation through the placenta where the mothers blood produces antibodies that affects the RhD positive and the baby is born with anemia.

72. True

73. True.

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