Complete the sentences below using the words and phrases provided to test your k

Question

Complete the sentences below using the words and phrases provided to test your knowledge of how chromatin in the eukaryotic chromosome can serve to regulate transcription. (Not all words and phrases are used.) Transcriptional activity can be kept at the simply due to the normal structure of chromatin in eukaryotes. In nucleosomes, modifications to the N-terminal can after chromatin structure and availablility of genes for transcription. of DNA at the cytosine of CG dinucleotides affects transcription and can be detected using restriction enzymes. can reposition or bump off the nucleosomes, making DNA and associated promoters and enhancers accessble. The addition of methyl groups to DNA and histone 3 can bring about that sliences transcription.

Explanation / Answer

1. transcription can be kept at the basal(minimal level)

2. Modifications to N-terminal histone tails

3. Methylation of DNA at cytosine of CG dinucleotides affects transcription

4. Chromatin remodelling complexes can reposition or bump off the nucleosomes

5, The addition of methyl group to DNA and histones can cause hypercondensation of chromatin

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