Suppose that the X-linked recessive condition Duchenne muscular dystrophy affect

Question

Suppose that the X-linked recessive condition Duchenne muscular dystrophy affects 1 in 3600 males in the United States. Assume that the only two alleles present are normal and disease-causing and that the population is in Hardy–Weinberg equilibrium. If the population of females in the United States is 160 million, how many females in the country do you expect to have the disease?

Question 19 of 21 Map sapling learning Suppose that the X-linked recessive condition Duchenne muscular dystrophy affects 1 in 3600 males in the United States. Assume that the only two alleles present are normal and disease-causing and that the population is in Hardy-Weinberg equilibrium. If the population of females in the United States is 160 million, how many females in the country do you expect to have the disease? Number females

Explanation / Answer

Hardy weinberg principle states that genotypic frequency in a population will remain constant from one generation to the other in absence of any external influences.

Expected genotype frequency for homozygotes = f(AA)=P2

=160,000,000(1/3600)2 =12

Aprox 12 females are expected to have this disease.

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