1. How many purines are in a 1.5 kb fragment of DNA? 2. DNA replication is bidir

Question

1. How many purines are in a 1.5 kb fragment of DNA?

2. DNA replication is bidirectional. Explain how both strands of the parental DNA molecule can serve as a template. 5. Compare and contrast the following aspects of DNA replication and transcription: Direction of new strand synthesis, Type of template strand, Site where processes is initiated, Site where the process is terminated, Enzyme required for the process.

6. A chromosome is 55 kbp long. After DNA replication in a cell without telomerase, how long is the chromosome? Assume that RNA primers are 10 nucleotides long.

8. Brown eye color in humans is promoted by the pigment, melanin. The HERC2 gene normally stimulates the production of melanin, while a mutant allele of HERC2 does not stimulate melanin and results in blue eyes. Do you think this mutant allele is dominant or recessive? Why?

10. A single enzyme is encoded by 4 different genes. Does this defy the Central Dogma? Why or why not?

Explanation / Answer

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So there are 1500 bases. Since A=T and G=C and since adenine and guanine are both purines, there will be 750 purines.

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