A study is being performed to see if there is a correlation between the concentr
ID: 72212 • Letter: A
Question
A study is being performed to see if there is a correlation between the concentration of chromium in the blood and a suspected disease. Blood samples from a series volunteers with a history of the disease and other indicators ot susceptibility are analyzed and compared with the results from the analysis samples from healthy control subjects. From the following results determine whether the differences between the two groups can be ascribe to chance or whether they are real. Control group (ppb Cr): 15, 23,12,18, 9, 28,,10. Disease group: 25, 20, 35, 32, 15, 40, 16, 10, 22,18.Explanation / Answer
Chromium (III), also called Cr (III), is an important nutrient that the body needs to process certain sugars, proteins and fats.
Chromium (III): Breathing chromium (III) does not irritate the nose or mouth in most people. There is not enough data to know if chromium (III) causes cancer. Eating small amounts of chromium (III) is healthy but eating too much is harmful. The recommended daily dose of chromium (III) is 50 -200 g. Chromium (VI): Breathing chromium (VI) at high levels can irritate the nose and cause sneezing, itching, nosebleeds, ulcers and holes in the nasal septum. It can also cause asthma attacks in people who are allergic to chromium. Long term exposure to high levels is linked to lung cancer. Breathing low levels of chromium (VI) for a short period does not cause health problems for most people. Eating small amounts of chromium (VI) is not harmful. However, eating or drinking large amounts in food or water can cause an upset stomach, ulcers, convulsions, and damage the kidneys and liver. This type of exposure can be fatal.
The levels of chromium present in biological tissues and fluids are extremely low (e.g., ca. 3-10 ppb in blood of mammals)
The blood samples reveal that the patients are suffering from a disease which is caused due to high concentration of chromium in blood
Diabetes is a common disease that affects 16 million people in the United States, with an estimated 800,000 new cases diagnosed each year.Chromium is an essential trace element for mammals, and Cr complexes have been used as a dietary supplement for the treatment of diabetes and its complications. Chromium deficiency has also been linked to increased risk of nonfatal myocardial infarction and cardiovascular disease.
Effects of high concentration of chromium in blood
The diseased patient may have complaints of “allergies” and sores on his hands and arms.The patient may notice the onset of runny nose, sinus drainage, dry cough, and occasional nosebleeds (both nares intermittently) for more than 2 or 3 months. No prior history of allergies exists. He may also have occasional nausea and is concerned because the sores and minor skin cuts on his hands do not seem to heal. The patient denies having fever, chills, dyspnea, or change in bowel or bladder habits, and he may notice excessive thirst or easy bruising. He may lose his appetite and lose weight without dieting.
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