Ebonia is a small country (population 32,000) in which many people can trace the

Question

Ebonia is a small country (population 32,000) in which many people can trace their ancestry to King Vulcan, who lived in the 12th century and liberated the Elbonians from the Geeks.

King Vulcan was known for having pointed ears and many Elbonians today have pointed ears. You have been hired by the Elbonian government to test whether having pointed ears is genetic and to find the gene or genes responsible.

You are able to confirm that the cause of pointed ears is recessive and a single gene is involved. Would autozygosity mapping be a good approach in this case? Why or why not?

Explanation / Answer

Yes autozygosity mapping is good approach for this case.This tool is used to identify ressively inherited disease.micro array SNP genotypes data are first used to identify auto zygous region. The disease gene is identified by sequencing the genes within the candidates disease loci

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