Two individuals (A and B) were infected with the HIV virus. Cells from individua

Question

Two individuals (A and B) were infected with the HIV virus. Cells from individual A express HLA-A11 and HLA-23 proteins, while cells from the individual B have HLA-A30 and HLA-A03. The peptides from the nef protein produced by the HTV virus, which can be presented by these MHC molecules, are shown below. Based on this information, please answer the following questions. Assume that these are the only MHC molecules expressed by these individuals, and nef is the only protein expressed by HIV. Given this information is correct, which individual would remain "symptom-free" longer after infection? Please explain your logic briefly. You observe that individual A remains symptom-free for 2 years after infection. However, you observe that another individual who is homozygous for HLA-A11. also remains symptom-free for 2 years after infection. Is this observation surprising? Please state yes or no. and explain your logic briefly.

Explanation / Answer

Yes information is correct

Nef protein produce during the early stage of infection, plays a crucial role in creating the perfect environment for viral reproduction and reduces the ability of infected cells to induce an immune response. But in intial stages there is rise in CD4 count due to infection and virus also increase their number but at low rate..

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