What is the difference between an instrument detection limit and a method detect

Question

What is the difference between an instrument detection limit and a method detection limit? (Select all that apply.)

What is the difference between robustness and intermediate precision?

The instrument detection limit is obtained by preparing and analyzing many independent samples. The method detection limit is obtained by replicate measurements of aliquots from one sample. There is more variability in the instrument detection limit, so it should be higher than the method detection limit. The method detection limit is obtained by preparing and analyzing many independent samples. The instrument detection limit is obtained by replicate measurements of aliquots from one sample. There is more variability in the method detection limit, so it should be higher than the instrument detection limit.

Explanation / Answer

1. There is more variability in the instrument detection limit, so it should be higher than the method detection limit.

2.Intermediate precision is the variation observed when an assay is performed by different people on different instruments on different days in the same lab.

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