These are allele frequencies for five loci, from three populations in the northe

Question

These are allele frequencies for five loci, from three populations in the northeastern USA, with space for a fourth population. In your calculations, you may round to two decimal places. 1. List the possible genotype for the PGM locus at the Bayonne site. 2. Using Hardy-Weinberg assumptions, calculate the expected genotype frequencies for PGM at Bayonne, and write them directly under your notations for the genotypes above, in your answer to question #1. 3. What proportion of individuals at Bayonne are expected to be heterozygous at the PGI-2 locus? 4. What proportion of individuals at Bayonne are expected to be heterozygous at the PGM locus? 5. Imagine you sampled a population on Staten Island and scored 60 plants for their genotypes at G6PD-1, finding: 30 aa, 24 ab, and 6 bb. Calculate the genotype frequencies and enter them in Table 2 below, under the Observed column.

Explanation / Answer

Assuming that answer is sought for the questions marked with a cross, because the calculations for the Q1 and Q2 are correct.

Answer 3: 0 (As explained below)

Since the frequency of allele b at Bayonne PGI-2 locus is 0, one cannot expect any heterozygotes. So the proportion of such individuals has to be zero.

Answer 4: 17/50. (As explained below)

The proportion of individuals at Bayonne expected to be heterozygous at PGM locus = (2pq + 2pr + 2qr) / 1 = 0.16 + 0.02 + 0.16) / 1 = 0.34 = 17/50.

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