Which study design was used to conduct this study? Be specific in describing the
ID: 78815 • Letter: W
Question
Which study design was used to conduct this study? Be specific in describing the study design (ie prospective cohort, experimental, case-control, etc). The pharmaceutical company who produces Lumigan (bimatoprost), a drug formulated to treat certain medical conditions of the eye, is studying secondary effects. Lumigan was put on the market six years ago to treat glaucoma. Anecdotal reports have surfaced about people who are treating their eye conditions with Lumigan but are growing very long eyelashes. The company wants to know if there is any truth to these reports so they can apply to the FDA for marketing rights in the cosmetics industry. You identify those people still alive who received either Lumigan or a placebo medication for glaucoma during the original pre-marketing phase, seven years ago. You conduct a study comparing photographs of people at the start of the pre-marketing phase to current photos to see how eyelash loss or growth compares between those who used Lumigan to those who got the placebo.
Explanation / Answer
The above study is "experimental -based randomized control study" in which subjects who have been under Lumigan treatment will be compared to the subjects who are under control or placebo groups. These results can be useful to test epidemiological hypothesis whether Lumigan is an effective drug in treating glaucoma. Therefore, "RCT" (simple randomized control design) and randomized trial: These two methods used synonymously. However, it has illustrated that RCT is pertaining to trail -experimental design that include control –Placebo groups. In this design, patient groups who are receiving experimental treatment compared with control groups (placebo groups).
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