You are interested in studying a gene called CFTR because mutations in this gene

Question

You are interested in studying a gene called CFTR because mutations in this gene in humans cause cystic fibrosis. You have made a line of mice that lack the mouse CFTR gene. These mice are unable to clear bacteria from their lungs, so they get lung disease. You put a normal human CFTR gene into some of these mice and discover that the mice with the human gene are able to clear bacteria from their lungs and no longer get lung disease. From this experiment, you can conclude that: ___ Question 19 options: A) The DNA sequences of the mouse CFTR gene and human CFTR gene are identical.

B) The amino acid sequences of the mouse CFTR protein and the human CFTR protein are identical.

C) The mouse CFTR gene and human CFTR gene encode proteins that can serve a similar function.

D) Both answers B and C are true.

E) All of the above are true.

Explanation / Answer

All of he above are true.

Mostmammalian genes have similar sequences and the products of those genes have similar functions. Hence animal experiments are done on mice.

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