Mandy is born with sickle cell disease to two normal parents. Mandy\'s sister Sa

Question

Mandy is born with sickle cell disease to two normal parents. Mandy's sister Samantha does not have sickle cell disease. What is the probability that Samantha is a carrier? SHOW YOUR WORK Given the cross GgHhliJJ x ggHhlijj what is the probability of offspring gg hhlijj? SHOW YOUR WORK A woman with type B blood marries a man with type A blood. Their first child has type 0 blood. The couple is expecting the ir next child. Draw a Punnett square showing the potential genotypes of the second child. Two dwarfs with achondroplasia decide to have children. What is the likelihood that their first living child will be of normal height? Show your work. A woman with hemophilia marries an unafflicted male. a. What are the genotypes of both parents? mom = dad = b. What is the probability of the two parents having a son with hemophilia as well? Show your work. Given the following recombination frequencies, determine the correct sequence of the following genes. (EFGHI) Show your work. E-F 12% E-G 2% E-H 7% E-l 12% F-G 10% F-H 19% F-l 24% G H9% G-l 14% H-l 5%

Explanation / Answer

Answer 5):

Since both parents are nomal phenotypically, but both carries the trait for sickle cell

Father(AS) X Mother(AS)
Has sickle cell trait - Carrier Has sickle cell trait - Carrier
One copy of sickle cell gene One copy of sickle cell gene

Child(Male) AA
Does not have SCA
Two cpoies of normal gene
Child(Female) AS
Has SCA trait -carrier
One copy of the Sickle hemoglobin gene
Child(Male) AS
Has sickle cell trait- carrier
One copy of sickle hemoglobin gene
Child(Female) SS
Has sickle cell anemia
Two copies of sickle cell hemoglobin gene

Since Samantha does not have sickle cell anemia there is 1/4 =0.25 or 25% probability that she is a carrier of the trait.

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