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Resveratrol is a natural compound found in red grapes (and red wine) and is thou

ID: 80280 • Letter: R

Question

Resveratrol is a natural compound found in red grapes (and red wine) and is thought to have beneficial effects in mammals, such as preventing tumor growth and delaying age-related diseases. In vitro, resveratrol and its derivatives have been shown to cause cell-cycle arrest in S phase and induce apoptosis. You have analyzed the DNA content of cultured cells in the presence and absence of these drugs using fluorescence-activated cell sorting. Compared with control cells (dashed line), which of the following curves do you think better represents the DNA content of cells treated with these compounds?

Explanation / Answer

(D) Compared with the control cells, the curve D best represent the DNA content of cells treated with Resveratrol. The graph best describes the mean growth of the cells exponentially (DNA increase) and the linear line showing a decrease in the cell population.

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