What is the general mechanism for the initiation of translation in eukaryotes? S

Question

What is the general mechanism for the initiation of translation in eukaryotes? Select one: a. The preinitiation complex including small subunit of ribosome binds to the 5' cap of the mRNA and scans the mRNA for the initiation codon. b. The large subunit of the ribosome and initiation factors bind to the 5' cap of the mRNA and scans the mRNA for the initiation codon. c. The ribosome binds to the initiation codon on the mRNA molecule. d. The small subunit of the ribosome binds to the ribosome binding site on the mRNA molecule.

Explanation / Answer

A) the. Protein factors bind the small unit of ribosomal unit I.e 40s in eukaryotes. A factor called eIF3 is present with 40s ribosomal subunit. This eIF3 prevents premature binding of larger subunit of ribosome to mRNA

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