Compound A is soluble in water and methylene chloride (CH2Cl2). The partition co

Question

Compound A is soluble in water and methylene chloride (CH2Cl2). The partition coefficient K for A is 10:1 (CH2Cl2:water. A is initially dissolved in 60mL of water. We want to maximize the amount of A extracted into CH2Cl2. What is the best way to do this?

a. extract the water layer three times with 20mL of CH2Cl2 and combine the CH2Cl2 extract

b. extract the water layer two times with 30mL CH2Cl2 and combine the CH2Cl2 extract

c. extract the water layer one time with 60mL of CH2Cl2

d. all of the above will give the same total amount of A extracted into CH2Cl2

Explanation / Answer

d)

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