Think of the major places in the body where triacylglycerols are encountered and

Question

Think of the major places in the body where triacylglycerols are encountered and need to be hydrolyzed. Two of the items should not be placed in the bins.

The first step in the metabolism of triacylglycerols is the hydrolysis of the ester linkage by a lipase. Three different lipases play major roles in triacylglycerol metabolism in animals: pancreatic lipase (a water-soluble lipase secreted into the intestine), lipoprotein lipase, and hormone sensitive lipase. Identify the properties, location, and other characteristics of these lipases by dragging the items to the appropriate bins. Some of the items may not apply to any of these lipases, in which case leave that item unsorted.

Explanation / Answer

1) Pancreatic Lipase

---> hydrolyzes dietary triacylglycerols

-------> requires bile salts for activity

2) Lipoprotein lipase

-----> located in blood capillaries

-----> stimulated by glucagon

------> hydrolyzes adipose triacylglycerols

3) HOrmone -sensitive protein

------> stimulated by epinephrine

------> also hydrolyzes cholesterol esters

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