6. What was the primary goal of the Human Genome Project? a. Mapping known disea
ID: 83600 • Letter: 6
Question
6. What was the primary goal of the Human Genome Project?
a. Mapping known disease genes to loci on their chromosomes
b. Studying the human proteome
c. Sequencing the genomes of humans and common lab organisms
d. Mutational analysis of the human genome
e. Sequencing the human microbiome
7. A branch of genomics that generates three-dimensional structures from their amino acid sequences is known as
a. bioinformatics b. comparative genomics
c. structural genomics d. pharmacogenomics e. Pharmacogenetics
8. If two genes are suspected to be linked and a test cross is performed to measure their position on a chromosome,
How many cM or Mu are there between the genes based on the data from the following cross?
Gg,Rr X gg,rr GR phenotype = 34% gr phenotype = 36% Gr phenotype = 12% gR phenotype = 18%
a. 30 cM b. 12 cM c. 70 cM d. 18 cM e. 66 cM
9. Some people are unable to properly metabolize the drug Purinethol, which is given to patients with acute lymphoblastic leukemia; therefore, such patients must be first tested for the associated genetic variant to determine proper dosage of the drug. This scenario best illustrates the use of _____.
a. pharmacogenomics b. map-based sequencing c. positional cloning
d. annotation of DNA sequences e. comparative genomics
10. After completion of a genome sequencing project, the DNA sequences are analyzed to locate and identify genes in a process called _____.
a. automation b. comparative genomics c. physical mapping d. compilation e. annotation
Explanation / Answer
6) What was the primary goal of the Human Genome Project?
c. Sequencing the genomes of humans and common lab organisms.
HGP(Human Genome Project) was initiated in the year 1990. The main purpose of the project was to determine the DNA sequence of the entire euchromatic human genome in the time period of 15 years. In the project along with the human genome study, other animals were also studied such as bacteria H.influenzae, E.coli genome, yeast etc. So option c is the most appropriate answer.
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