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(4 of4) What is the origin of the regioselectivity in the hydroboration reaction

ID: 855726 • Letter: #

Question

(4 of4) What is the origin of the regioselectivity in the hydroboration reaction? (A) Rearrangement of a carbocation intermediate; (B) steric reasons: the less substituted carbon is less sterically hindered and therefore is more accessible for boron to bind; (C) electronic reasons: the less substituted carbon is more electronegative. A B C A and B A and C B and C (3 of4) Which product would you expect to obtain from the following reaction: (2 of4) Which of the following solvents can be used to carry out the hydroboration-oxidation reaction? A B C D E B, and C D, and E B, C, and D B, C, and E B and E B and C (1 of4) Select the statements that correctly describe the region and stereochemical outcome of the hydroboration-oxidation reaction: (A) syn-addition of H-B species; (B) anti-addition of H-B species (C) hydrogen adds first, followed by rearrangement of the resulting carbocation to a more stable species, then boron adds last; (D) oxidation step (cleavage of C-B and formation of C-O bond) is accompanied by inversion of configuration; (E) oxidation step (cleavage of C-B and formation of C-O bond) is accompanied by retention of configuration; A, C, and D B, C, and D A and D B and C A and E B and E

Explanation / Answer

1) A and E

2) B and C

3)A

4) B and C