PLEASE, URGENT: I need a step-by-step solution to these questions. Please and th
ID: 856056 • Letter: P
Question
PLEASE, URGENT: I need a step-by-step solution to these questions. Please and thank you!
A pharmacist receives a medi-cation order for 300,000 units of penicillin G potassium to be added to 500 mL of D5W. The directions on the 1,000,000-unit vial state that if 1.6 mL of solvent are added, the solution will measure 2 mL. How many milliliters of the solution must be withdrawn and added to the D5W?
17. A medication order calls for acyclo-vir, 355 mg, to be administered by intravenous infusion over 60 minutes. A 500-mg vial of acyclovir is avail-able that must be mixed with sterile water for injection to prepare 10 mL of injection. The proper amount is then admixed with 100 mL of nor-mal saline solution. Calculate (a) the volume to be taken from the vial of mixed acyclovir, (b) the rate of infu-sion in mL/min, and (c) the drops/min if using an intravenous set that delivers 20 drops/mL.
19. A medication order calls for a dopa-mine drip at 5 mg/kg/min for a 185-lb patient. The pharmacy adds 400 mg dopamine in 250 mL of D5W. Calculate the drip rates per minute when using administration sets delivering:
(a) 15 drops/mL
(b) 20 drops/mL
(c) 60 drops/mL
A solution containing 500,000 units of polymyxin B sulfate in 10 mL of sterile water for injection is added to 250 mL of 5% dextrose injection. The infusion is to be administered over 2 hours. If the administration set delivers 15 drops/mL, at what rate, in drops per minute, should the flow be adjusted to administer the infusion over the designated time interval?
An 8-kg infant requires a continuous infusion of a drug to run at 1 mL/hour to deliver 4 mcg of drug/kg per minute. Calculate the milligrams of drug that must be added to a 100-mL intravenous infusion solution.
29. A hospital pharmacist prepared thirty 100-mL epidural bags containing 0.125% of bupivacaine hydrochlo-ride and 1 mg/mL of fentanyl citrate in 0.9% sodium chloride injec-tion. How many (a) 30-mL vials of 0.5% bupivacaine hydrochloride, (b) 20-mL vials of 50 mg/mL of fen-tanyl citrate, and (c) 1-L bags of 0.9% sodium chloride were required?
If a physician orders 5 units of insulin to be added to a 1-liter intravenous solution of D5W to be administered over 8 hours, (a) how many drops per minute should be administered using an IV set that delivers 15 drops/mL, and (b) how many units of insu-lin would be administered in each 30- minute period?
Using the nomogram in Figure 13.5, determine the approximate rate of infusion delivery, in drops per min-ute, based on 1.5 liters of fluid to be used over a period of 8 hours with an infusion set calibrated to deliver 16 drops/mL.
The recommended maintenance dose of aminophylline for children is 1 mg/kg/hr by injection. If 10 mL of a 25 mg/mL solution of aminophyl-line is added to a 100-mL bottle of dextrose injection, what should be the rate of delivery, in milliliters per hour, for a 40-lb. child?
A patient is receiving 500 mL of an intravenous drip containing 25,000 units of sodium heparin in sodium chloride injection. Calculate (a) the administration rate, in mL/h, to deliver 1200 units of sodium heparin per hour and (b) the administration rate, in drops/min, with an IV set that delivers 15 drops/mL.
If the loading dose of phenytoin in children is 20 mg/kg of body weight to be infused at a rate of 0.5 mg/kg/min, over how many minutes should the dose be administered to a 32-lb. child?
If a medication order calls for a dobutamine drip, 5 mg/kg/min, for a patient weighing 232 lb. what should be the drip rate, in drops per minute, if the 125-mL infusion bag contains 250 mg of dobutamine and a micro-drip chamber is used that delivers 60 drops/mL?
A pharmacist places 5 mg/mL of acy-clovir sodium in 250 mL of D5W for parenteral infusion into a pediatric patient. If the infusion is to run for 1 hour and the patient is to receive 500 mg/m2 BSA, what would be the rate of flow in milliliters per minute for a patient measuring 55 cm in height and weighing 10 kg?
An intravenous infusion contains 5 mg of RECLAST (zoledronic acid) in 100 mL. If the infusion is to be administered in 15 minutes, how many (a) milligrams of zoledronic acid, and (b) milliliters of infusion must be administered per minute? And (c), using a drip-set that delivers 20 drops/milliliter, how many drops per minute must be infused?
TORISEL (temsirolimus), for use in advanced renal cell carcinoma, is pre-pared for infusion by adding 1.8 mL of special diluent to the drug vial resulting in 3 mL of injection con-taining 10 mg/mL of temsirolimus. The required quantity is then added to a 250-mL container of sodium chloride injection for infusion. The recommended dose of temsirolimus is 25 mg infused over 30 to 60 min-utes. The quantity of drug delivered, in mg/mL, and the rate of infusion, in mL/min, for a 30-minute infusion are: (a) 0.099 mg/mL and 8.42 mL/min (b) 0.099 mg/mL and 8.33 mL/min (c) 1 mg/mL and 8.42 mL/min (d) 1 mg/mL and 8.33 mL/min
The mAb (myoclonal antibody) eculizumab is available in 30-mL vials containing 300 mg of drug. Prior to administration by intravenous infusion, the solution is diluted with sodium chloride injection to a concentration of 5 mg/mL. The dose of eculizumab is 600 mg infused over a 35-minute period. Calculate the rate of infusion in drops/min using an administration set that deliv-ers 15 drops/mL.
Explanation / Answer
1.
1.8 g sodium chloride
40 g dextrose
3.. 50 drops/minute
5. 8 hours, 20 minutes
7. 500 minutes
9. 5 mL lidocaine injection
11. 1344 mL IVIG
13. 0.6 mL
15. 1.8 mL amikacin sulfate injection
17.
(a) 7.1 mL
(b) 1.785 or 1.8 mL/minute
(c) 35.7 or 36 drops/minute
19.
(a) 3.9 or 4 drops/minute
(b) 5.25 or 5 drops/minute
(c) 15.7 or 16 drops/minute
20.
(a) 41.7 or 42 drops/minute
(b) 166.7 mL/hour
21.
1.1 mL
52.8 mg
23. 40 drops/minute
25. 32.6 or 33 drops/minute
27. 192 mg
29.
(a) 25
(b) 3
(c) 3
31.
(a) 31.25 or 31 drops/minute
(b) 0.3 unit
33. approximately 50 drops/minute
35. 8 mL/hour
37.
(a) 24 mL/hour
(b) 6 drops/minute
39. 40 minutes
41. 15.82 or 16 drops/minute
43. 0.58 mL/minute
45.
(a) 0.33 mg zoledronic acid
(b) 6.67 mL
(c) 133 drops/minute
47. (a) 0.099 mg/mL and 8.42 mL/minute
49. 51.4 or 51 drops/minute
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