The following reaction (let\'s label it \"Rxn A\") requires energy to proceed: g

Question

The following reaction (let's label it "Rxn A") requires energy to proceed:

glucose + Pi - - > glucose-6-phosphate + H2O

In light of the need for energy input in the synthesis of glycose-6-phosphate, how can we account for the fact that reaction 1 of glycolysis is spontaneous?

A. Rxn A is coupled by hexokinase to the synthesis of ATP from ADP and Pi.

B. Rxn A is coupled by hexokinase to the hydrolysis of ATP to ADP and Pi.

C. Rxn A is coupled by hexokinase to cAMP formation from ATP.

D. None of the above.

Explanation / Answer

A. Rxn A is coupled by hexokinase to the synthesis of ATP from ADP and Pi

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