which of A small generic section of the primary structure of an helix is given b
ID: 884667 • Letter: W
Question
which of A small generic section of the primary structure of an helix is given below. -amino acid-amino acidz-amino acids-amino acid4-amino acids-amino acids-amino acidy- (a) Which amino acid residue's backbone forms a hydrogen bond with the backbone of the second (2nd) residue? Choose the correct residue from the drop-down menu. amino acid [sele anmer amino acid (Select answe (b) Which of the following peptide segments is most likely to be part of a stable helix at physiological pH? O-Gly-Gly-Gly-Ala-Gly- O-Lys-Lys-Ala-Arg-Ser- O-Tyr-Trp-Phe-Val-lle- -Glu-Glu-Glu-Glu-Glu- O Glu-Leu-Ala-Lys-Phe- O -Gly-Arg-Lys-His-Gly- O -Pro-Leu-Thr-Pro-Trp-Explanation / Answer
a)
the rule for this is n+4 rule
Answer: amino acid 6
b)
Answer: -Glu-Leu-Ala-Lys-Phe-
Here we need to decrease the repulsion force. SO 2 negative and 2 positive should be as far as possible.
positively charged residues are usually 3 AA acids away from negatively charged residues as well as aromatic AA
Proline and Glycine do not like to form alpha helices because proline is bulky and glycine is too flexible
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