Order the initial steps of Merrifield\'s peptide synthesis procedure. Enter the

Question

Order the initial steps of Merrifield's peptide synthesis procedure. Enter the step number (1-6) in the box. Remove protecting group from attached amino acid's a-amino group. Attach Fmoc-protected C-terminal amino acid to resin by its carboxyl group. Add 2^nd amino acid with DCC-activated carboxyl group. alpha-amino group of 1st amino acid attacks the activated carboxyl group of the 2nd amino acid. Repeat the cycle by adding the next amino acid in the peptide sequence (a-amino group is Fmoc- protected; a-carboxyl group is DCC-activated). Wash away the unreacted amino acid.

Explanation / Answer

1) attach Fmoc-protected

2) remove protecting group..

3)add 2nd amino acid with...

4) alpha amino group of 1st amino acid

5) wash away the unreacted amino acid

6) repeat the cycle

Related Questions

Navigate

• Browse (All)
• Browse O
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.