Tay Sachs is a recessive lethal disease in which there is a neurological deterio

Question

Tay Sachs is a recessive lethal disease in which there is a neurological deterioration early in life. This disease is rare in the population but is found in high frequency in Ashkenazi Jews from Central Europe. A woman whose maternal uncle had the disease is trying to determine the probability that she and her husband could have an affected child. The woman's father does not come from a high-risk population. The woman's husband's sister of the disease at an early age. a. Draw the pedigree of the individuals described. Include genotypes where possible (Call the alleles T and t).

Explanation / Answer

The pedigree you have drawn above is correct.

When only one of the parent is a carrier and another parent has no disease, then there is no chance the child will be affected with Tay Sachs disease. Thats why the woman will be unaffected because only her mother was the carrier. And the woman's husband is also the only carrier among them, so their child will be free from disease. But with every pregnancy, there are 50% chances of the child being a carrier of the disease.

Related Questions

Navigate

• Browse (All)
• Browse T
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.