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6. In human ABO blood typing, there are three alleles possible (I A , I B , i) t

ID: 90349 • Letter: 6

Question

6. In human ABO blood typing, there are three alleles possible (IA, IB, i) that result in four blood types (A, B, AB, and O).

a) If one parent phenotype is type A blood and the other type B blood, and they have four children who represent all of the blood types, what are the genotypes of the parents?

b) Could a child of type O blood have a type A father and a type AB mother?

c) If the first child is type A blood, and his parents are type AB and type O, what is the chance that the second child would have type A blood?

Explanation / Answer

6. In human ABO blood typing, there are three alleles possible (IA, IB, i) that result in four blood types (A, B, AB, and O).

three different alleles, IA, IB, and i.

IA and IB alleles are codominant,

the i allele is recessive

Type A --------genotype -------IAIA or IA IO

Type B --------genotype--   IBIB, or IB IO

Type O --------genotype   -----IO IO

a) If one parent phenotype is type A blood and the other type B blood, and they have four children who represent all of the blood types, what are the genotypes of the parents?

Type A --------genotype -------IAIA or IA IO

Type B --------genotype--   IBIB, or IB IO

Type O --------genotype   -----IO IO

one parent phenotype is type A blood and the other type B blood

Type A --------genotype ------- IA IO

and the other type B blood

Type B --------genotype IB IO

IA IO            X      IB IO

IA

IO

IB

IA IB           Type AB

IO IB       Type B

IO

IA IO      Type A

IO     IO              Type O

PARENTS    GROUPS ARE

Type A --------genotype ------- IA IO

Type B --------genotype IB IO

b) Could a child of type O blood have a type A father and a type AB mother?

No

Type O --------genotype   -----IO IO

genotype   -----IO IO                is not possible

c) If the first child is type A blood, and his parents are type AB and type O, what is the chance that the second child would have type A blood?

Type A --------genotype -------IAIA or IA IO

Type AB --------genotype -------IA IB

Type O --------genotype   -----IO IO

genotype -------IA IB X      genotype   -----IO IO

IA

IB

IO

IA IO

IB IO

IO

IA IO

IB IO

what is the chance that the second child would have type A blood?

EVERY ISSUE IS NEW AND INDEPENDENT EVENT

ONE ISSUE DOESNOT AFFECT NEXT ISSUE

HENCE

chance that the second child would have type A blood = 50%= 0.5 ANSWER

IA

IO

IB

IA IB           Type AB

IO IB       Type B

IO

IA IO      Type A

IO     IO              Type O

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