A new drug is produced in a bioreactor. The process is termed batch operation, s

Question

A new drug is produced in a bioreactor. The process is termed batch operation, since the reactants are added all at the beginning, the system is sealed and the reaction takes place, and then the products are removed. Within this processing system, the concentration of drug in the reactor increases as thereaction proceeds. Consider an accounting equation that tracks the drug only during the time that the reaction is occurring. Is the system open or closed or isolated? Is the system dynamic or steady state? Is the system reacting or nonreacting? What time of accounting equation would be used: differential, algebraic or integral? Is the property conserved?

Explanation / Answer

Is the system open or closed or isolated?

In case of batch culture, substances required for the reactions is put together and system is allowed to complete the reaction. Thereafter, the products are removed. However, energy is Thus, it is close system.

Is the system dynamic or steady state?

In this example, the system is in dynamic state, as the reactions are continuous going on.

Is the system reacting or nonreacting?

Of course, system is reacting that’s why the product is forming.

What time of accounting equation would be used: differential, algebraic or integral? Is the property conserved?

According to Hatzis et al. (1995), has given a algebraic differential equation for multivariable to describe the relation between time and cell concentration. However in this condition property is changing continuously till the arrival of steady state.

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