From your experience with TLC, would you say that silica gel should be considere

Question

From your experience with TLC, would you say that silica gel should be considered relatively polar or relatively non-polar? Explain-cite convincing experimental data to support your answer. Draw the three different plates you would expect from obtaining a TLC from acetaminophen on silica gel using ethyl ether, hexane, or ethanol as eluting solvents. Explain the trend. Draw the three different plates you would expect from obtaining a TLC from ibu -profen on silica gel using toluene, ethyl acetate, and methanol as the eluting solvents. Explain the trend. Two substances have the same R_f upon TLC analysis. Is this proof that the two substances have the same molecular weight? Explain. Two substances have the same Rf upon TLC analysis. Is this proof that the two substances have the same functional groups? Explain. Label the functional groups in each of the compounds shown below.

Explanation / Answer

a)A more polar sample will bind to the stationary phase silica gel , and will not move far . A nonpolar sample will move faster and faraway.So in 1st case silica gel is relatively non polar & 2nd case silica gel is relatively polar

b)As we know the more polar the eluent, the faster and farther move the sample. In question polarity oder of eluent is given as-

methanol> ethyl acetate> toulene.If same sample is sparated using silica gel as the stationary phase and methanol, ethyl acetate & toulene as eluent . then the sample move faster and farther in metanol, less farther in ethyl acetate & list in toulene.

c) a-OH-, C=ONH2,

b-C=O, COOH-

c-OH-, NH=

d--CO-,OH

Related Questions

Navigate

• Browse (All)
• Browse F
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.