In some cases, neurotransmitter will bind to a receptor and activate a G protein

Question

In some cases, neurotransmitter will bind to a receptor and activate a G protein whose function is to activate adenylate cyclase. Adenylate cyclase converts ATP to cAMP, which leaves the plasma membrane to go into the cell and activate a protein kinase A. Protein kinase A phosphorylates K^+ channels, causing them to close. Based on this information, which of the following statements is correct? The initial receptor was indirectly linked to the K^+ channel. Protein kinase A is the second messenger in this pathway. This response pathway would lead to an IPSP The K^+ channel is a voltage-gated channel.

Explanation / Answer

The potassium (K+) channels are membrane proteins that allow selective flow of K+ ions across the cell membrane, and generates electrical signals in cells. They open and close upon changes in the transmembrane potential.

The correct statements would be:
Protein kinase A is the second messenger in this pathway.
this response pathway would lead to an inhibitory postsynaptic potential (IPSP).
The K+ channel is a voltage-gated channel.

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