Which of the following apply to reactions displaying sigmoidal kinetics? The enz
ID: 96020 • Letter: W
Question
Which of the following apply to reactions displaying sigmoidal kinetics?
The enzymes catalyzing these reactions are composed of multiple subunits.
The Vmax and K0.5 of the enzymes catalyzing these reactions can be increased or decreased through interactions with allosteric effectors or by covalent modification.
Small changes in substrate concentration can result in large changes in the velocity of the reaction.
a and b.
a, b, and c.
a.The enzymes catalyzing these reactions are composed of multiple subunits.
b.The Vmax and K0.5 of the enzymes catalyzing these reactions can be increased or decreased through interactions with allosteric effectors or by covalent modification.
c.Small changes in substrate concentration can result in large changes in the velocity of the reaction.
d.a and b.
e.a, b, and c.
Explanation / Answer
(d) a and b
The third statement (c) cannot be predicted in terms of allosteric enzymes because binding of a substrate or nonsubstrate molecule to the active allosteric site of enzyme can also enhance its activity or can also impair its activity. It is not confirmed due to multiple active sites in the enzyme.
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