In about 25% of all breast cancer cases, the cancer cells have somehow made extr
ID: 96822 • Letter: I
Question
In about 25% of all breast cancer cases, the cancer cells have somehow made extra copies of a gene called HER2. The extra gene copies cause these cells to have too many copies of the protein encoded by the gene. The excess HER2 proteins cause the cells to be cancerous.
A new drug called Herceptin is given to breast cancer patients who have been diagnosed to have the excess HER2 protein in their breast cancer cells. Herceptin binds to these proteins and prevents the cancer cells from dividing and spreading.
Herceptin drug must be....
a specific primer sequence that binds to the HER2 gene.Explanation / Answer
Answer: (c) an antibody that can bind specifically to the HER2 protein.
Explanation:
Herceptin is a humanized monoclonal antibody that acts by binding to HER2 receptor and inhibiting its activity and the corresponding downstream signaling cascades. Herceptin flags the tumor cell for destruction by the body's immune system.
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