Glucosamine, shown below, is a competitive inhibitor of the enzyme hexokinase, w

Question

Glucosamine, shown below, is a competitive inhibitor of the enzyme hexokinase, which catalyzes the phosphorylation of glucose in the first step of glycolysis (Eqn. 1 below). Which statement best describes the inhibition by glucosamine?

Glucosamine reacts with glucose, preventing glucose from binding to the active site of hexokinase.

Glucosamine binds to the active site of hexokinase, preventing glucose from binding.

Glucosamine stabilizes the active site of hexokinase, preventing glucose 6-phosphate from being released.

Glucosamine binds to the surface of hexokinase, causing a change in shape of the enzyme and the active site, preventing glucose from binding.

Explanation / Answer

Statement 2 has explained well.if copetitive binder it'll compete with the other molecule by binding to active side of enzym

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