A patient with lymphoma is receiving rituximab. When explaining possible side ef

Question

A patient with lymphoma is receiving rituximab. When explaining possible side effects to a patient, the nurse understands that side effects of this drug are: a greatest with the fourth dose. b related to the site of the target antigen. c due to proteasome 265 inhibition. d cumulative in nature. The International Agency for Research on Cancer publishes: a evidence indicating increased occurrence of cancer among nurses. b independent assessments of the carcinogenic risk of chemicals c definition, classification, and toxicity of hazardous drugs. d safe level of occupational exposure to hazardous drugs.

Explanation / Answer

53) Rituximab is a monoclonal antibody used in the treatment of leukemias and lymphomas. The side effects of Rituximab include head ache, chills, pain, nausea, vomiting and stomach burn. Most of the side effects of Rituximab is due to IgM flare produced during infusion. IgM flares gradually decreases over time. Therefore, the side effects of Rituximab therapy is due to proteasome 26s inhibition (option c).

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