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1- Which of these biomolecules are NOT lipids? a) oils b) fats c) fatty acids d)

ID: 1021554 • Letter: 1

Question

1- Which of these biomolecules are NOT lipids?

a) oils

b) fats

c) fatty acids

d) triglycerides

e) steroids (including cholesterol)

f) none of the above

3- Which of the following statements are FALSE with respect to the prognosis and complications of familial hypercholesterolemia?

a) The outcome is likely to be poor in people with the homozygote type of familial hypercholesterolemia because it causes early heart attacks and is resistant to treatment.

b) Heart attacks may occur at an early age in patients

c) The disease is associate with cholesterol-rich deposits in skin, eyelids

d) In families with a history of familial hypercholesterolemia, genetic counseling may be of benefit, especially if both parents are affected.

e) none of the above

4- Which of these lipids are esters that can be hydrolyzed to give fatty acids along with other products including an alcohol?

a) waxes

b) fats

c) oils

d) glycerophospholipids

e) all of the above

5-Lipids of physiologic importance for humans have which of the following important functions?

a) important structural roles in cells and cell membranes

b) function as padding and for insulation

c) provision of the hydrophobic barrier that permits partitioning of the aqueous contents of cells and subcellular structures.

d) a major source of energy for the body, and a source of fuel for muscles.

e) provide fuel and energy reserves, predominantly in the form of triacylglycerols.

f) all of the above

6-Preventive antioxidants include

a) catalase

b) peroxidases that react with ROOH

c) chelators of metal ions such as DTPA (diethylenetriaminepentaacetate)

d) EDTA (ethylenedi amine-tetraacetate).

e) all of the above

7- Isoprenoid molecules and their derivatives are precursors of

a) cholesterol

b) Ubiquinone (coenzyme Q)

c) All the fat- soluble vitamins A, D, E, and K

d) The long-chain alcohol dolichol

e) Beta carotene (provitamin A).

f) all of the above

8. Which one of the following enzymes is NOT involved in the degradation of total dietary lipid during digestion?

A. Gastric lipase

B. Pancreatic lipase

C. Lipoprotein lipase

D. Phospholipase A2

E. Cholesterol ester hydrolase

9 The free fatty acid present in the plasma is transported in association with:

A. Albumin

B. HDL

C. LDL

D. VLDL

E. Chylomicrons

10 Which one of the following statements about prostaglandins is INCORRECT?

A. Prostaglandins have a very short half-life.

B. Prostaglandins are synthesized only in the liver and the adrenal cortex.

C. Prostaglandins generally act locally on or near the tissue that produced them.

D. The common precursor of the prostaglandins is arachidonic acid.

E. Prostaglandin synthesis can be inhibited by a number of unrelated compounds including cortisol and aspirin.

11. Which one of the following has as one of its major effects the ability to inhibit platelet aggregation?

A. Leukotriene A4

B. Prostacyclin

C. Thromboxane A2

D. Prostaglandin H2

E. Arachidonic acid

12-One of the characteristics of each of the sphingolipidoses is the absence or deficiency of a specific catabolic enzyme activity. These enzymes are normally localized in the:

A. Golgi complex.

B. lysosomes.

C. endoplasmic reticulum.

D. mitochondria.

E. cytosol.

           

13 Which one of the following compounds is a precursor in the biosynthesis of cholesterol?

A. Coprostanol

B. Progesterone

C. Lanosterol

D. Cholic acid

E. Pregnenolone

14 Which one of the following changes would you expect in a patient with decreased activity of lipoprotein lipase?

A. Elevation of plasma chylomicrons only.

B. Elevation of both plasma chylomicrons and very low density lipoproteins.

C. Elevation of plasma HDL only.

D. Elevation of plasma LDL only.

E. Elevation of both plasma HDL and LDL.

15. Which of these statements are TRUE with respect to the storage role of lipids?

a) When attached to glycerol, fatty acids may be stored as triglycerides (fat), which acts as an emergency reserve.

b) Operationally, gram for gram of stored triglyceride has far less mass than an energetically equivalent store of starch.

c) Fats and oils are used by living cells for only one purpose to store energy.

d) Because there are more calories per gram for fat than for any other nutrient, more energy can be stored in less space as fat.

e) all of the above

f) none of the above

16. A patient with high blood cholesterol levels was treated with lovastatin. This drug lowers blood cholesterol levels because it inhibits

A absorption of dietary cholesterol

B lipoprotein lipase in adipose tissue

C citrate lyase in liver

D VLDL excretion by the liver

E HMG CoA reductase in liver and peripheral tissues

           

17-Which one of the following statements about plasma lipoproteins is correct?

A. Chylomicrons are synthesized primarily in adipose tissue and transport triacylglycerol to the liver.

B. HDL particles are produced from low-density lipoprotein particles (LDL) in the circulation by the action of lipoprotein lipase.

C. Very low density lipoprotein particles (VLDL) are the precursors of LDL in the circulation.

D. HDL competes with LDL for binding to receptors on the surface of cells in extrahepatic tissues.

E. Cholesteryl ester transfer protein in HDL is important for the efficient uptake of cellular cholesteryl esters by HDL in extrahepatic tissues.

18. In the human, prostaglandins can be derived from

A glucose

B acetyl CoA

C arachidonic acid

D oleic acid

E leukotrienes

19Which of these lipids are particularly important cell membrane constituents in the nervous system?

a) gangliosides

b) cerebrosides

c) shingomyelins

d) all of the above

e) a and c only

20 Which of the following statements apply/applies to eicosanoids?

a. The mechanisms by which aspirin and glucocorticosteroids inhibit prostaglandin formation in tissues are different.

b. The endoperoxide prostaglandin H2 is the precursor of prostaglandin E2, prostaglandin F2alpha, prostaglandin I2 (prostacyclin) and thromboxane A2.

c. Regulation of phospholipase A2-catalyzed hydrolysis of glycerophospholipids to yield free polyunsaturated fatty acids may provide a general mechanism for controlling PG synthesis.

d. The half-lives of many PGs are very short.

e   all of the above are correct

Explanation / Answer

1.Answer:option f

I.e all options a to e are lipids.

Lipids are a class of organic compounds which includes fatty acids and their derivatives. Theese are insoluble in water but soluble in organic solvent.Eg: oil, fats, wax, steroids, fatty acids, mono di and tri glycerides etc