Certain antibodies have been shown to only bind to the folded structure of their

Question

Certain antibodies have been shown to only bind to the folded structure of their target protein ligand, yet others will bind to both the folded and denatured states of the same protein ligand.

a contiguous amino acid sequence

continuous

regions of the protein that are distant in primary sequence, but close in the folded structure

discontinuous

In the former case, the binding epitope is composed of______ (a _____ epitope).

In the latter case, the binding epitope is composed of ______ (a _____ epitope).

Explanation / Answer

An epitope is the specific target to which an antibody binds. Within a given protein sequence, there are two tyeps of epitopes,

Thus the solutions are as follows.

In the former case, the binding epitope is composed of regions of proteins that are distant in pimary sequence but close in the folded structure (a discontinuous epitope)

In the latter case, the binding epitope is composed of a contiguous amino acid sequence (a continuous epitope)

Related Questions

Navigate

• Browse (All)
• Browse C
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.