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Rett Syndrome is a dominant x-linked disease. Assuming a mother who is heterozyg

ID: 11425 • Letter: R

Question

Rett Syndrome is a dominant x-linked disease. Assuming a mother who is heterozygous and a father who does not have the disease. (a) What is the probability that they will have a child (of either sex) who has Rett Syndrome? (b) What is the probability that they will have a son with Rett Syndrome? (c) What is the probability that they will have a daughter with Rett Syndrome?
*Can you please show me how to get the answer as well as telling me what the answer is?

**Also, if you answer the other questions I posted about Fabry disease, I forgot to add that Fabry is a recessive x-linked condition.

Explanation / Answer

     a mother--------- -------------genotype ----------- X X

father-------------AFFECTED ------------------- genotype ----------- XR Y

GAMETES

XR

Y

X

XR X    

X Y

X

XRX   

XY

(a)    What is the probability they will have a child (of either sex) who has Rett Syndrome?

50%

(b)   What is the probability they will have a son with Rett syndrome?

0%

(c) What is the probability they will have a daughter with Rett syndrome?

100%

GAMETES

XR

Y

X

XR X    

X Y

X

XRX   

XY

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