Rett Syndrome is a dominant x-linked disease. Assuming a mother who is heterozyg
ID: 11425 • Letter: R
Question
Rett Syndrome is a dominant x-linked disease. Assuming a mother who is heterozygous and a father who does not have the disease. (a) What is the probability that they will have a child (of either sex) who has Rett Syndrome? (b) What is the probability that they will have a son with Rett Syndrome? (c) What is the probability that they will have a daughter with Rett Syndrome?*Can you please show me how to get the answer as well as telling me what the answer is?
**Also, if you answer the other questions I posted about Fabry disease, I forgot to add that Fabry is a recessive x-linked condition.
Explanation / Answer
a mother--------- -------------genotype ----------- X X
father-------------AFFECTED ------------------- genotype ----------- XR Y
GAMETES
XR
Y
X
XR X
X Y
X
XRX
XY
(a) What is the probability they will have a child (of either sex) who has Rett Syndrome?
50%
(b) What is the probability they will have a son with Rett syndrome?
0%
(c) What is the probability they will have a daughter with Rett syndrome?
100%
GAMETES
XR
Y
X
XR X
X Y
X
XRX
XY
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