Rett Syndrome is a dominant x-linked disease. Assuming a mother who is non-disea

Question

Rett Syndrome is a dominant x-linked disease. Assuming a mother who is non-diseased and a father who has Rett-Syndrome. (a) What is the probability they will have a child (of either sex) who has Rett Syndrome? (b) What is the probability they will have a son with Rett syndrome? (c) What is the probability they will have a daughter with Rett syndrome?
*Can you show me how to get the correct answer as well as showing me the correct answer?

*If you answer the other questions about Fabry disease, I forgot to include that Fabry disease is a recessive x-linked condition.

Explanation / Answer

     a mother--------- -------------genotype ----------- X X

father-------------AFFECTED ------------------- genotype ----------- XR Y

GAMETES

XR

Y

X

XR X    

X Y

X

XRX   

XY

(a)    What is the probability they will have a child (of either sex) who has Rett Syndrome?

50%

(b)   What is the probability they will have a son with Rett syndrome?

0%

(c) What is the probability they will have a daughter with Rett syndrome?

100%

GAMETES

XR

Y

X

XR X    

X Y

X

XRX   

XY

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