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Below is a short sequence of a transcript encoding the stop codon and C- termina

ID: 133027 • Letter: B

Question

Below is a short sequence of a transcript encoding the stop codon and C- terminal amino acids of a protein: 5'- ...CAACUGCCUGACCCACACUUAUCACUAAGUAGCCUAGCAGUCUGA The resulting amino acid sequence contains the amino acid Asn encoded by the codon 5'-CAA-3' The remainder of the amino acids are encoded in the same reading frame: N...Asn-Cys-Leu-Thr-His-Thr-Tyr-His-C The c-terminal ends of two mutant proteins produced by alleles of this gene are as follows: Mutant 1: N...Asn-Cys-Leu-Thr-His-Thr-Tyr-His-Lys-C Mutant 2: N...Asn-Cys-Leu-Thr-His-Thr-Tyr-His-Tyr-Ser-Ser-Leu-Ala-Val-C Select ALL of the statements that apply to these observations: A Mutant 1: Lys was added to the mutant polypeptide and is encoded by AAA or AAG B. Mutant 2: nsertion of an A nucleotide into the codon for the 2nd HIS shifted the reading frame. C. Mutant 1: Deletion of the U from the WT stop codon would produce an AAG codon followed by a UAG stop codon. 1 DMutant 2: Deletion of the G from the stop codon could produce a Tyr.

Explanation / Answer

option A and option C are correct.

Lys was added to the mutant polypeptide and is encoded by AAA or AAG.

Deletion of the U from the WT stop codon would produce an AAG codon followed by a UAG stop codon.

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