opulations. As in the n Rious disease are very likel man evolution n selection t
ID: 135719 • Letter: O
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opulations. As in the n Rious disease are very likel man evolution n selection to alter allele fre- eakereen individual humans will in contrast, increased mobility ulations question 15-5: A serine-tryptophan polymorphism in the ptation the nthe 3 gene affects aloin taste sensitivity, with a tryptophan at position 35 being the sensitive allele. (a) Using the UCSC Genome Browser,identify the ancestral amino acid at this polymorphism. (b) The plants of the genus Aloe contain aloin and grow n i-arid conditions. Given your answer to part (a),suggest a hypothesis for the evolution of this polymorphism. er of uestion 15-6: The United Nations predicts that the human lobal population is most likely to stabilize at 9 billion within e next 100 years. If the population level remains at this level for the next 10 KY, what would you predict about the following e of th parameters, compared to today's values? (a) Effective population size. (b) Average heterozygosity. (c) The strength of selection required to overcome effects of genetic drift. (d) FST between populations. Over the same time-scale, the chimpanzee population declines to 400 individuals, and remains stable thereafter. 200 chimpanzees are kept as an interbreeding population across the world's zoos, whi ile 200 remain as wild in a nature reserve. In these instances, how will the four parameters (a-d) change?Explanation / Answer
Question 15-5:
a) Ancestral amino acid is serine in both alleles and when one of them or both have Tryptophan sensitivity is there.
b) Aloin is a better substance which is present in Aloe Vera. In humans, bitter taste is mediated by TAS2R43 which belongs to a family of G protein-coupled receptors,hT2Rs. People who have the above-mentioned mutation are known to be very sensitive to bitter taste. Bitterness signifies toxicity which one can encounter from frutis, nuts, vegetables, accidently from ointments etc therefore this allele might have evolved during evolution to give protection to humans from harmful environmental insults.
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