28-y/o former life-long vegan comes to you saying he has experienced itchy eyes,

Question

28-y/o former life-long vegan comes to you saying he has experienced itchy eyes, a red rash and tingling of the mouth twice in the past two months. He tells you he has no history of anything like this, but that he did recently start eating shellfish. The first meal was fine, but a month later he ate shelfish for a second tiíme, this time drenched in butter, resulting in a reaction. Because of this he tells you he is lactose intolerant. (a) What type of hypersensitivity does he have AND what is a common name for it? (b) What food caused the reaction? (c) Explain the timing of the reaction. (d) What molecules and cells are involved? (e) What are two ways his reactions/symptoms can be prevented? () What is one way he can be cured of the affliction AND what molecule are you trying to make more of in his body? (g) Why might it be important to know that he is an only child that grew up in the city?

Explanation / Answer

Answer2:

(a) He has type I hypersensitivity and commonly named as allergy.

(b) Shellfish caused the reaction.

(c) During first intake of shellfish he developed IgE antibody against allergen, IgE molecules attached to the mast cells. When second time he take shellfish the IgE primed mast cell burst and releases granules and chemical such as histamines.

(d) Molecule IgE , plasma cells and mast cells are involved.

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