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Go back to the NOVA page at http://www.pbs.org/wgbh/nova/sciencenow/3210/02.html

ID: 14257 • Letter: G

Question

Go back to the NOVA page at http://www.pbs.org/wgbh/nova/sciencenow/3210/02.html
Click on “The RNAi Cure”.

RNAi has great potential for the treatment of disease where targeting of specific mRNAs can serve as an effective approach. Although therapeutic RNAi is still in the very early stages, it provides hope that cures for many devastating diseases may be on the horizon.

Multiple trials are currently underway for using RNAi in the treatment of disease in humans.

12. (1 point) What is the name of a human disease being considered for treatment using RNAi? What is the key hurdle to getting RNAi to work for this condition? If no hurdles are described for the condition you chose, say what specific gene is being targeted instead.

Explanation / Answer

12. (1 point) What is the name of a human disease being considered for treatment using RNAi?

hepatitis cancer , AIDS etc

What is the key hurdle to getting RNAi to work for this condition?

dicing

silening if desired genes

If no hurdles are described for the condition you chose, say what specific gene is being targeted instead.

post transcitional modification

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