Response To Questions Part A To B (Please Not Using Online Information For Your

Question

Response To Questions Part A To B (Please Not Using Online Information For Your Response) A. The protein will have to compensate for a valine (orange color represent valine) in the image below on the surface. Would it be possible for the valine to "flip around" and burv itself inside the core? B. Explain whv hemoglobin (whole structure in the image below represent hemoglobin forms long chains or "fibers" of tetramer aggregates in response to a valine (orange color represent valine) in the image below or Educational Use Unly

Explanation / Answer

A) It is not possible for the valine to flip around and bury itself inside the core. Because it has a large uncharged, non polar side chain. So, it prefers to stay outside the alpha helix. If it flips inside, the large structure will disrupt the helix.

B) Valine is non polar and it forms a van der Waals interactions with a leucine on residue no 88 or phenylalanine on residue no 85 of an deoxygenated beta subunit of haemoglobin. The molecules stick together to develop long chains or fibers of tetramer aggregates,as Hb has 2 alpha chains and 2 beta chains.

Related Questions

Navigate

• Browse (All)
• Browse R
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.