Holliday intermediates in homologous genetic recombination differ from those in
ID: 148588 • Letter: H
Question
Holliday intermediates in homologous genetic recombination differ from those in site-specific recombination based on whether branch migration typically occurs Choose the statements below that describe this difference in mobility throughout the genome. Mobile Holliday intermediates form only on prokaryotic chromosomes, while immobile Holliday intermediates form on eukaryotic chromosomes Branch migration can occur along the homologous sequences of paired chromosomes. Branch migration in site-specific recombination is generally restricted by the presence of heterologous sequences flanking the recombination site. DNA ligase fails to seal the nicks in mobile Holliday intermediates. Branch migration only occurs when replication stalls to force replication enzymes through the stopping point.Explanation / Answer
Answer:
Brach migration in site-specific recombination is generally restricted by the presence of heterologous sequences flanking the recombination site.
Branch migration can occur along homologous sequence of paired chromosome.
Explanation:
In site specific recombination, branch migration occur between the recombination sites with no extensive homology.
Mobile Holliday intermediates are formed in both prokaryotes and eukaryotes chromosomes. Immobile Holliday intermediates are artificially made for scientific study.
DNA ligase seals the nick in Holliday intermediates.
Brach migration can occur spontaneously.
Related Questions
drjack9650@gmail.com
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.