What is the most likely outcome of a mutation that introduced an AUG codon twelv

Question

What is the most likely outcome of a mutation that introduced an AUG codon twelve nucleotides upstream (5') of the original AUG start codon in a mammalian mRNA?

A. No protein

B. No effect on translation

C. Translation would initiate at the new AUG codon, but the protein product would likely be truncated (shortened) due to a change in reading frame.

D. Translation would initiate at the new AUG codon and the original protein would be synthesized, however, it would have an additional five amino acids added on at the N-terminus.

E. All of the above

Explanation / Answer

Answer - (D) AUG is the start codon.

If by mutation additional AUG inderted 12 nuckeotide upstream then translation process would initiate at the new AUG codon and the origunal protein would be synthesised , however it would have an additional five amino acids added on the N- terminal.

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