a 74 y/o lifetime xenophobic, agoraphobic, life long vegetarian had been experie

Question

a 74 y/o lifetime xenophobic, agoraphobic, life long vegetarian had been experiencing increasing dementia during the last few years. As a germaphobe she literally lives in a bubble by herself. She feared infectious diseases so much that all her food was grown in her protected greenhouse free from all infectious particles. her brain biopsy showed aggregation of certain proteins and hollow areas within the brain, but PCR and RT-PCR came back negative for pathogen DNA/RNA a. what was the agent that killed her? (b) what is the whole disease name? (c) how was it contracted? (d) what molecular test could be done to verify its identity? (e) what related disease has been found I cattle, particularly in the U.K. (use the medical term, not the media's name for it)?

Explanation / Answer

a. A protein called prion is the causative agent.

b. Transmissible spongiform encephalopathy, also known as prion disease.

c.It is a neuro degenerative fatal brain disease contracted through the consumption of infected cattles meat or other products.

d.Western blotting, ELISA through Chemiluminescence, and FCS, MUFS through Fluorescence apart from EEG and MRI.

e. Bovine spongiform encephalopathy

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