Consider the pedigree below showing a rare (not commonly found in the population

Question

Consider the pedigree below showing a rare (not commonly found in the population) X-linked recessive trait. Assume no spontaneous mutations in this family and 100% penetrance. In the first generation, the man is unaffected and the woman is affected. Individuals indicated by letters in subsequent generations may or may not be affected. Choose your answer(s) carefully since you will receive credit only if you select all possible correct answers. If individual A also showed the trait (was shaded in), which of this children would have a 50% chance of being affected? If none of the individuals would 50% chance of being affected, then select "Q". A B C D E F G H I J K L M N O P Q

Explanation / Answer

Answer: Option Q

When a male individual with X linked recessive trait (aY) marries unaffected women (AA) then children will show one of two genotypes.All sons will be carrying AY, Y chromosome from father and A allele from mother while all daughters will be heterozygous aA carrier. They will not be carrying the trait but can pass it on to its children.Hence none of the children of individual A with X linked recessive trait will be carrying X linked recessive trait.

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