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Eukaryotic messenger RNA can undergo post synthetic processing after transcripti

ID: 174109 • Letter: E

Question

Eukaryotic messenger RNA can undergo post synthetic processing after transcription and before translation. One of the processing steps is splicing, where portions of the RNA are removed and the remaining RNA joined together. Sort the following statements regarding mRNA splicing as true or false.

Eukaryotic messenger RNA can undergo post synthetic processing after transcription and before translation. One of the processing steps is splicing, where portions of the RNA are removed and the remaining RNA joined together. Sort the following statements regarding mRNA splicing as true or false. True statements False statements Splicing occurs while the mRNA Splicing occurs after the m enters the cytoplasm RN is attached to the spliceosome. but before it binds to the ribosome Proteins in the splicesome recognize the 5 and 3' splice site sequences The spliceosome consists of One mRNA can sometimes code five small RNA molecules for more than one protein land many associated proteins. by splicing at alternative sites.

Explanation / Answer

True statements -

- splicing occurs while the mRNA is attached to spliceosome.

- small RNAs in the spliceosome recognise the 5' and 3' splice sites

- One mRNA can code for more than one protein by splicing at alternative sites.

- The spliceosome consists five small RNA molecules and many associated proteins.

False statements

- in splicing, exon sequences are removed in the form of lariat formation and are degraded.

- splicing occurs after it enters the cytoplasm but before it binds to the ribosome.

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