A 22-year-old male undergoes workup for recent history of hemoptysis. A chest ra

Question

A 22-year-old male undergoes workup for recent history of hemoptysis. A chest radiograph reveals bilateral diffuse alveolar infiltrates. He has no other symptoms. Serologic tests reveal antiglomerular basement membrane antibodies. Which of the following statements is true regarding this disease?

A) With current therapeutic options including steroids and plasmapheresis, the prognosis is good.

B) Immunofluorescence of the lung would reveal granular deposits within the pulmonary vessels.

C) Biopsy of the lung would reveal red blood cells and hemosiderin-laden macrophages within the airspaces.

D) Pulmonary symptoms occur a few days before findings of renal involvement and disease

Explanation / Answer

Answer:

The following statements are true regarding this diseases are

B) Immunoflurescence of the lung would reveal granular deposits within the pulmonary vessicle

D) Pulmonary symptoms occurs a few days before finding of renal involvement and disease

The answer B is true as anti-GBM antibodies are observed and can be detected using indirect immunofluorescence .

The answer D is true as anti-GBM disease is involves both pulmonary and renal disease

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